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ZFP42 / REX-1

ZFP42 zinc finger protein

Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal.

Gene Name:	ZFP42 zinc finger protein
Synonyms:	ZFP42, HREX-1, Reduced expression protein 1, REX1, ZFP42 zinc finger protein, Zinc finger protein 42, Zinc finger protein 754, ZNF754, Zinc finger protein 42 homolog, REX-1, REX1 transcription factor, Zfp-42
Target Sequences:	NM_174900 NP_777560.2 Q96MM3

Publications (1)

Progesterone-dependent deoxyribonucleic acid looping between RUSH/SMARCA3 and Egr-1 mediates repression by c-Rel. Hewetson A, Chilton BS. Molecular endocrinology (Baltimore, Md.). 2008 22:813-22. [PubMed:18174357] [PMC:PMC2276468]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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