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ZFP36L1

ZFP36 ring finger protein-like 1

ZFP36L1 is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: ZFP36 ring finger protein-like 1
Synonyms: ZFP36L1, Berg36, Butyrate response factor 1, Early response factor Berg36, ERF-1, ERF1, EGF-response factor 1, Protein TIS11B, RNF162B, TIS11B, CMG1
Target Sequences: NM_004926 NP_004917.2 Q07352

Publications (1)

1
mRNA destabilizing factors: tristetraprolin expression at the porcine maternal-fetal interface. Kasra Khalaj, Jocelyn M Wessels, Rami T Kridli, Mallikarjun Bidarimath, Jonathan LaMarre, Chandrakant Tayade. American journal of reproductive immunology (New York, N.Y. : 1989). 2015 May;73:402-16. [Full Text Article] [PubMed:25496016] Related Antibodies: LS-C144647.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).