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ZFP36L1 is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: | ZFP36 ring finger protein-like 1 |
Synonyms: | ZFP36L1, Berg36, Butyrate response factor 1, Early response factor Berg36, ERF-1, ERF1, EGF-response factor 1, Protein TIS11B, RNF162B, TIS11B, CMG1 |
Target Sequences: | NM_004926 NP_004917.2 Q07352 |
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