XRCC3

X-ray repair complementing defective repair in Chinese hamster cells 3

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment; the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junctions of replication forks. Involved in HJ resolution and thus in processing HR intermediates late in the DNA repair process; the function may be linked to the CX3 complex and seems to involve GEN1 during mitotic cell cycle progression. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.

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Products

Proteins (14)

Type

Over-Expression Lysate (9)

Recombinant (5)

Target

XRCC3 (14)

Publications

No (14)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-SUMO (1)

Myc-DDK (Flag) (9)

Species

Human (10)

Source

293T Cells (5)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human XRCC3 Protein (Recombinant GST) (Full Length) - LS-G30919

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.69 kDa

Price:

2 µg/$439

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XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124020

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

100 µg/$494

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Human XRCC3 Protein (Recombinant GST, N-terminus) (aa31-130) - LS-G60533

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118869

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

100 µg/$494

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XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118870

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

100 µg/$494

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Human XRCC3 Protein (Recombinant His) - LS-G2092

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human XRCC3 Protein (Recombinant His-SUMO) (Full Length) - LS-G21329

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

53.83 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human XRCC3 Protein (Recombinant His, N-Terminal) (Asp2-His346) - LS-G96937

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

40 kDa

Price:

10 µg/$265; 100 µg/$365; 250 µg/$518; 50 µg/$315

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Human XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80484

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

20 µg/$150

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Human XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80485

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

20 µg/$150

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Human XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80486

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

20 µg/$150

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Human XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80487

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

20 µg/$150

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Human XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80488

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

20 µg/$150

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XRCC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100545

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.7 kDa

Price:

100 µg/$494

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