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Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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XCR1

chemokine (C motif) receptor 1

XCR1 is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: chemokine (C motif) receptor 1
Family/Subfamily: GPCR , Chemokine
Synonyms: XCR1, CCXCR1, Chemokine (C motif) receptor 1, Chemokine XC receptor 1, G protein-coupled receptor 5, GPR5, Lptn receptor, Lymphotactin receptor, XC chemokine receptor 1, G-protein coupled receptor 5
Target Sequences: NM_005283 NP_005274.1 P46094

Publications (3)

1
Gene expression profiles in the bovine corpus luteum (CL) during the estrous cycle and pregnancy: Possible roles of chemokines in regulating CL function during pregnancy. Sakumoto R, Hayashi KG, Hosoe M, Iga K, Kizaki K, Okuda K. The Journal of reproduction and development. 2015 61:42-8. (IHC; Bovine) [Full Text Article] [PubMed:25382605] [PMC:PMC4354230]
2
The role of the chemokine receptor XCR1 in breast cancer cells. Yang XL, Qi LG, Lin FJ, Ou ZL. Breast Cancer (Dove Med Press). 2017 9:227-236. (IHC; Human) [Full Text Article] [PubMed:28408852] Related Antibodies: LS-C178854.
3
A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability. Bird EV, Iannitti T, Christmas CR, Obara I, Andreev VI, King AE, Boissonade FM. Neuroscience. 2018 May;379:334-349. [Full Text Article] [PubMed:29588250] [PMC:PMC5953414] Related Antibodies: LS-A158.

☰ Filters
Antibodies (50)
Primary (50)
XCR1 (50)
Human (42)
Mouse (8)
Monkey (8)
IHC (29)
IHC-P (28)
WB (20)
Flo (3)
ELISA (18)
ICC (1)
rabbit (47)
goat (3)
Product Group
GPCR Database Antibodies (28)
IHCPlus (27)
PathPlus Cancer (1)
IgG (11)
polyclonal pc (50)
AP Conjugated (5)
APC (1)
APC Conjugated (6)
Azide-free (5)
Biotin Conjugated (6)
CF Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (7)
Unconjugated (11)
Extracellular Domain (14)
C-Terminus (8)
aa305-333 (8)
Cytoplasmic Domain (7)
aa43-222 (7)
N-Terminus (2)
aa1-31 (1)
aa244-322 (1)
No (48)
Yes (2)
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$425
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (Biotin) Antibody
Human
IHC, IHC-P
Biotin Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (FITC) Antibody
Human
IHC, IHC-P
FITC Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (AP) Antibody
Human
IHC, IHC-P
AP Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (APC) Antibody
Human
IHC, IHC-P
APC Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (PE) Antibody
Human
IHC, IHC-P
PE Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$425
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (Biotin) Antibody
Human
ELISA, IHC, IHC-P
Biotin Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (FITC) Antibody
Human
ELISA, IHC, IHC-P
FITC Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (APC) Antibody
Human
ELISA, IHC, IHC-P
APC Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (AP) Antibody
Human
ELISA, IHC, IHC-P
AP Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Extracellular Domain) (PE) Antibody
Human
ELISA, IHC, IHC-P
PE Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$425
XCR1 Antibody - Anti-XCR1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) (FITC) Antibody
Human, Monkey
IHC, IHC-P
FITC Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
XCR1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) (Azide-free) (HRP) Antibody
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
XCR1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) (PE) Antibody
Human, Monkey
IHC, IHC-P
PE Conjugated
100 µl/$650
XCR1 Antibody - Anti-XCR1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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XCR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC-P
Unconjugated
50 µg/$425
XCR1 Antibody
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XCR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$265
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XCR1 Goat anti-Human Polyclonal (N-Terminus) (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$665
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XCR1 Goat anti-Human Polyclonal (N-Terminus) (CF) Antibody
Human
Flo
CF Conjugated
100 Tests/$575
XCR1 Antibody - Western blot of XCR1 antibody.
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XCR1 Rabbit anti-Mouse Polyclonal (aa244-322) Antibody
Mouse
WB
Unconjugated
100 µl/$255; 200 µl/$285; 500 µl/$415; 1 ml/$485
XCR1 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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XCR1 Rabbit anti-Human Polyclonal Antibody
Human, Monkey
ELISA, IHC, WB
Unconjugated
100 µl/$325; 200 µl/$375
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XCR1 Rabbit anti-Human Polyclonal (aa305-333) (AP) Antibody
Human
ELISA, WB
AP Conjugated
200 µl/$740
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XCR1 Goat anti-Human Polyclonal (aa1-31) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$770
Viewing 1-25 of 50 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).