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XCL1 / Lymphotactin
chemokine (C motif) ligand 1
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.
| Gene Name: | chemokine (C motif) ligand 1 |
| Family/Subfamily: | Intercrine , Intercrine gamma |
| Synonyms: | XCL1, ATAC, C motif chemokine 1, Chemokine (C motif) ligand 1, Cytokine SCM-1, Cytokine scm, LPTN, SCM-1, SCM-1-alpha, SCM-1a, SCM1, SCYC1, Scyc2, Single cysteine motif 1a, Lymphotaxin, Xc chemokine ligand, LTN, Lymphotactin, SCM1A, Small-inducible cytokine C1, XC chemokine ligand 1 |
| Target Sequences: | NM_002995 NP_002986.1 P47992 |
Publications (3)
1
Targeting Influenza Virus Hemagglutinin to Xcr1+<sup> Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses. Gudjonsson A, Lysén A, Balan S, Sundvold-Gjerstad V, Arnold-Schrauf C, Richter L, Bækkevold ES, Dalod M, Bogen B, Fossum E. Journal of immunology (Baltimore, Md. : 1950). 2017 April;198:2785-2795. [Full Text Article]
[PubMed:28228559]
2
Traumatic brain injury in mice induces changes in the expression of the XCL1/XCR1 and XCL1/ITGA9 axes. Agata Ciechanowska, Katarzyna Popiolek-Barczyk, Katarzyna Ciapala, Katarzyna Pawlik, Marco Oggioni, Domenico Mercurio, Maria-Grazia de Simoni, Joanna Mika. Pharmacological reports : PR. 2020 December;72:1579-1592. [Full Text Article]
[PubMed:33185818]
[PMC:PMC7704520]
3
A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza. Ranveig Braathen, Heidi Cecilie Larsen Spång, Daniëla Maria Hinke, Jana Blazevski, Sonja Bobic, Even Fossum, Bjarne Bogen. Molecular Therapy Methods & Clinical Development. 2020 Jan;17:378-392. [Full Text Article]
[PubMed:32128342]
[PMC:PMC7044496]
☰ Filters
Products
Proteins
(14)
Type
Over-Expression Lysate
(2)
Recombinant
(12)
Target
XCL1 / Lymphotactin
(14)
Publications
No
(14)
Tag
Fc/6His,C-terminus
(1)
Fc-6His, C-terminus
(1)
GST, N-terminus
(1)
His
(2)
His-GST, N-terminus
(1)
His-T7
(2)
Myc-DDK (Flag)
(2)
Species
Human
(10)
Mouse
(2)
Rat
(1)
Source
293T Cells
(1)
E. coli
(9)
HEK 293 Cells
(1)
Human Cells
(1)
Mammalian Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(4)
Low Endotoxin Level
Low endotoxin level
(4)
Biologically Active
Biologically active
(4)
E. coli
None
Biologically active
10.1 kDa
5 µg/$282; 500 µg/$2,095; 100 µg/$1,116
Human Cells
Fc-6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.4kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
12.52 kDa
100 µg/$494
E. coli
His
14.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
293T Cells
Myc-DDK (Flag)
12.52 kDa
20 µg/$150
E. coli
None
Biologically active
10.2 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
His-GST, N-terminus
42.3 kDa
50 µg/$490; 10 µg/$289; 200 µg/$977; 100 µg/$782; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
10.0 kDa
5 µg/$268; 20 µg/$349
E. coli
His-T7
13.0 kDa
10 µg/$283; 50 µg/$455; 100 µg/$727; 200 µg/$910; 1 mg/$2,026; 500 µg/$1,562; 5 mg/$3,179; 2 mg/$2,214
E. coli
His-T7
13.3 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~10 kDa
20 µg/$432; 1 mg/$4,915
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
Mammalian Cells
Fc/6His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.4 kDa
10 µg/$288; 50 µg/$436
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