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XAGE1E
X antigen family, member 1E
XAGE1D is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants.
| Gene Name: | X antigen family, member 1E |
| Synonyms: | XAGE1E, CT12.1D, CTP9, GAGED2, G antigen family D member 2, XAGE1, X antigen family, member 1D, XAGE1D, Cancer/testis antigen 12.1, CT12.1, Protein XAGE-1 |
| Target Sequences: | NM_020411 NP_065144.2 Q9HD64 |
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