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WNT7A

wingless-type MMTV integration site family, member 7A

WNT7A is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.

Gene Name: wingless-type MMTV integration site family, member 7A
Family/Subfamily: WNT , not assigned-WNT
Synonyms: WNT7A, Protein Wnt-7a, Proto-oncogene Wnt7a protein
Target Sequences: NM_004625 NP_004616.2 O00755

Publications (1)

1
Activation of AcvR1-Mediated Signaling Results in Semilunar Valve Defects. Shabber Syed, Sudha Rajderkar, Jeffrey M Mann, Travis Hawkins, Bingrou Wu, Bin Zhou, Yukiko Sugi, Yuji Mishina, Vesa Kaartinen. Journal of cardiovascular development and disease. 2022 August;9: [Full Text Article] [PubMed:36005436] [PMC:PMC9410128] Related Antibodies: LS-C335567.

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
WNT7A (6)
No (6)
His (2)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (3)
Purified (3)
Low endotoxin level (3)
Biologically active (2)
WNT7A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
39 kDa
100 µg/$494
WNT7A Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
35.5 kDa
3 µg/$268; 15 µg/$349
WNT7A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
39 kDa
20 µg/$150
Select
E. coli
317 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
34.98 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein.
The 318 amino acids recombinant protein has a predicted molecular mass 35.5 kD. The predicted N-terminal amino acid is Leu.
3 µg/$272; 15 µg/$352
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).