WNT5A

wingless-type MMTV integration site family, member 5A

Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.

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Products

ELISA Kits (12)

Type

Development Kit (3)

Sandwich (8)

Sandwich CLIA (1)

Target

WNT5A (12)

Reactivity

Human (6)

Mouse (5)

Rat (3)

Product Group

DevKit DuoPlus (3)

Format

96-Well Strip Plate (9)

Antibody Pair and Standard (3)

Publications

No (11)

Yes (1)

Sample Type

Cell Culture Supernatants (8)

Cell Lysates (6)

Plasma (6)

Serum (6)

Tissue Homogenates (10)

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Human WNT5A (Sandwich ELISA) ELISA Kit - LS-F55068

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Mouse WNT5A (Sandwich ELISA) ELISA Kit - LS-F35768

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human WNT5A (Sandwich ELISA) ELISA Kit - LS-F35770

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human WNT5A (Sandwich ELISA) ELISA Kit - LS-F12975

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Rat WNT5A (Sandwich ELISA) ELISA Kit - LS-F15714

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse WNT5A (Sandwich ELISA) ELISA Kit - LS-F15715

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse/Human/Rat WNT5A (Sandwich ELISA) ELISA Kit - LS-F6742

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse, Human, Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$811

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Mouse WNT5A (Sandwich ELISA) ELISA Kit - LS-F53480

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

3.12 - 200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Human WNT5A (CLIA) ELISA Kit - LS-F38871

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

13.7 - 10000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$911

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DevKit DuoPlus Mouse WNT5A ELISA Development Kit - LS-F72106

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,302; 1000 Wells/$1,947

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DevKit DuoPlus Human WNT5A ELISA Development Kit - LS-F72064

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,276; 1000 Wells/$1,903

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DevKit DuoPlus Rat WNT5A ELISA Development Kit - LS-F72232

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,356; 1000 Wells/$2,037

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