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WNT3

wingless-type MMTV integration site family, member 3

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

Gene Name: wingless-type MMTV integration site family, member 3
Family/Subfamily: WNT , not assigned-WNT
Synonyms: WNT3, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3, INT4, WNT-3 proto-oncogene protein
Target Sequences: NM_030753 NP_110380.1 P56703

Publications (2)

1
Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. Kraushar ML, Viljetic B, Wijeratne HR, Thompson K, Jiao X, Pike JW, Medvedeva V, Groszer M, Kiledjian M, Hart RP, Rasin MR. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 35:10911-26. (WB; Human) [Full Text Article] [PubMed:26245956] [PMC:PMC4524969] Related Antibodies: LS-B3241.
2
Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs. Yongkyu Park, Midori Lofton, Diana Li, Mladen-Roko Rasin. Cells. 2021 Jan;10:253. [Full Text Article] [PubMed:33525513] [PMC:PMC7911671] Related Antibodies: LS-C774904.

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Products
Antibodies (58)
Primary (58)
WNT3 (58)
Human (57)
Mouse (20)
Rat (6)
Bat (5)
Bovine (5)
Chicken (4)
Chimpanzee (3)
Dog (5)
Gibbon (3)
Goat (1)
Guinea pig (4)
Horse (5)
Monkey (4)
Pig (5)
Rabbit (4)
Sheep (1)
Xenopus (4)
Zebrafish (1)
IHC (18)
IHC-P (6)
WB (58)
ELISA (13)
IF (2)
Peptide-ELISA (2)
rabbit (36)
mouse (20)
goat (2)
Product Group
IHCPlus (1)
IgG (14)
IgG1 (11)
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IgG2b (2)
monoclonal mc (20)
polyclonal pc (38)
OTI1C5 (2)
OTI1C7 (2)
OTI1D9 (2)
OTI1F6 (2)
OTI1G7 (2)
OTI2A4 (2)
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OTI3F5 (2)
OTI3G5 (2)
APC (1)
APC Conjugated (3)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 594 Conjugated (1)
Azide-free (1)
Biotin Conjugated (5)
Carrier-free (9)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
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Unconjugated (32)
aa128-355 (12)
aa59-355 (8)
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aa143-192 (4)
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aa315-329 (1)
No (56)
Yes (2)
WNT3 Antibody - Anti-WNT3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
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WNT3 Goat anti-Human Polyclonal (aa315-329) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Mouse, Dog, Bovine, Bat, Rat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
WNT3 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-WNT3 mouse monoclonal antibody.
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WNT3 Mouse anti-Human Monoclonal (OTI1G7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
WNT3 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-WNT3 mouse monoclonal antibody.
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WNT3 Mouse anti-Human Monoclonal (aa128-355) (Carrier-free) (OTI1G7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
WNT3 Antibody - Western blot of WNT3 antibody.
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WNT3 Rabbit anti-Human Polyclonal (aa59-355) Antibody
Human
WB
Unconjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352
WNT3 Antibody - Immunohistochemistry analysis using Rabbit Anti-WNT3 Polyclonal Antibody. Tissue: Breast. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-WNT3 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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WNT3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µg/$442
WNT3 Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-WNT3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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WNT3 Mouse anti-Human Monoclonal (aa128-355) (OTI1C5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
WNT3 Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-WNT3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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WNT3 Mouse anti-Human Monoclonal (aa128-355) (Carrier-free) (OTI1C5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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WNT3 Goat anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC-P, WB
Unconjugated
0.1 mg/$518
WNT3 Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-WNT3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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WNT3 Mouse anti-Human Monoclonal (aa128-355) (OTI3G5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
WNT3 Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-WNT3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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WNT3 Mouse anti-Human Monoclonal (aa128-355) (Carrier-free) (OTI3G5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
WNT3 Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-WNT3 mouse monoclonal antibody.
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WNT3 Mouse anti-Human Monoclonal (OTI1F6) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
WNT3 Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-WNT3 mouse monoclonal antibody.
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WNT3 Mouse anti-Human Monoclonal (aa128-355) (Carrier-free) (OTI1F6) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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WNT3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
WNT3 Antibody - Western Blot Positive WB detected in: mouse kidney tissue All lanes: Wnt3 antibody at 3.2µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 40 kDa Observed band size: 40 kDa
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WNT3 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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WNT3 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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WNT3 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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WNT3 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
WNT3 Antibody - Western blot detection of Wnt3 in CHO-K1 cell lysate (B) and CHO-K1 transfected by Wnt3 (A) cell lysate using Wnt3 mouse mAb (1:1000 diluted). Predicted band size: 40KDa. Observed band size: 45KDa.
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WNT3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
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WNT3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
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WNT3 Rabbit anti-Human Polyclonal (aa155-184) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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WNT3 Rabbit anti-Human Polyclonal (aa155-184) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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WNT3 Rabbit anti-Human Polyclonal (aa155-184) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
WNT3 Antibody - Immunohistochemistry analysis using Rabbit Anti-WNT3 Polyclonal Antibody. Tissue: Breast. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-WNT3 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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WNT3 Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Human
IHC, WB
APC Conjugated
100 µg/$478
WNT3 Antibody - Immunohistochemistry analysis using Rabbit Anti-WNT3 Polyclonal Antibody. Tissue: Breast. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-WNT3 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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WNT3 Rabbit anti-Human Polyclonal (PerCP) Antibody
Mouse, Human
IHC, WB
PerCP Conjugated
100 µg/$478
WNT3 Antibody - Immunohistochemistry analysis using Rabbit Anti-WNT3 Polyclonal Antibody. Tissue: Breast. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-WNT3 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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WNT3 Rabbit anti-Human Polyclonal (Atto 390) Antibody
Mouse, Human
IHC, WB
Atto 390 Conjugated
100 µg/$479
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).