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Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.
Gene Name: | wntless Wnt ligand secretion mediator |
Synonyms: | WLS, C1orf139, G protein-coupled receptor 177, Protein wntless homolog, MRP, Wntless homolog (Drosophila), EVI, GPR177 |
Target Sequences: | NM_024911 NP_079187.3 Q5T9L3 |
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