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WDYHV1

WDYHV motif containing 1

Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

Gene Name: WDYHV motif containing 1
Synonyms: WDYHV1, C8orf32, Nt(Q)-amidase, N-terminal Gln amidase, NTAQ1, WDYHV motif containing 1
Target Sequences: NM_018024 NP_060494.1 Q96HA8

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Products
Antibodies (9)
Primary (9)
WDYHV1 (9)
Human (9)
Mouse (5)
Bovine (3)
Horse (3)
Pig (3)
IHC (1)
IHC-P (1)
WB (9)
ELISA (4)
rabbit (9)
IgG (4)
polyclonal pc (9)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (3)
N-Terminus (4)
aa30-79 (4)
aa106-136 (1)
No (9)
WDYHV1 Antibody - Western blot. All lanes: WDYHV1 antibody at 6 ug/ml. Lane 1: Mouse heart tissue. Lane 2: MCF7 whole cell lysate. Lane 3: U251 whole cell lysate. Secondary antibody: Goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 24 kDa. Observed band size: 24 kDa.
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WDYHV1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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WDYHV1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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WDYHV1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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WDYHV1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
WDYHV1 Antibody - Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with C8orf32 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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WDYHV1 Rabbit anti-Human Polyclonal (aa106-136) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
WDYHV1 Antibody - Western blot of Human HepG2. WDYHV1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WDYHV1 Rabbit anti-Human Polyclonal (aa30-79) Antibody
Human
WB
Unconjugated
100 µl/$424
WDYHV1 Antibody - Western blot of Human HepG2. WDYHV1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WDYHV1 Rabbit anti-Human Polyclonal (aa30-79) (HRP) Antibody
Bovine, Pig, Horse, Human
WB
HRP Conjugated
100 µl/$469
WDYHV1 Antibody - Western blot of Human HepG2. WDYHV1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WDYHV1 Rabbit anti-Human Polyclonal (aa30-79) (Biotin) Antibody
Bovine, Pig, Horse, Human
WB
Biotin Conjugated
100 µl/$469
WDYHV1 Antibody - Western blot of Human HepG2. WDYHV1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WDYHV1 Rabbit anti-Human Polyclonal (aa30-79) (FITC) Antibody
Bovine, Pig, Horse, Human
WB
FITC Conjugated
100 µl/$469
Viewing 1-9 of 9 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).