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WDR83

WD repeat domain 83

Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

Gene Name: WD repeat domain 83
Synonyms: WDR83, MAPK organizer 1, MORG1, WD repeat domain 83
Target Sequences: NM_032332 NP_115708.1 Q9BRX9

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Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
WDR83 (8)
No (8)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
WDR83 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.2 kDa
20 µg/$150
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293T Cells
Myc-DDK (Flag)
34.2 kDa
20 µg/$150
WDR83 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.2 kDa
100 µg/$494
WDR83 Protein - 12.5% SDS-PAGE of human MORG1 stained with Coomassie Blue
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Wheat Germ Extract
GST
60.7 kDa
10 µg/$479; 25 µg/$670
WDR83 Protein - Purified recombinant protein WDR83 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
34.2 kDa
20 µg/$1,107
WDR83 Protein - Purified recombinant protein WDR83 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
34.2 kDa
20 µg/$1,107
WDR83 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
WDR83 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.2 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).