WDR77 / MEP50

WD repeat domain 77

Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

WDR77 / MEP50 (5)

Publications

No (5)

Tag

GST (1)

His, N-Terminal (1)

His-SUMO (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human WDR77 / MEP50 Protein (Recombinant His-SUMO) (aa1-312) - LS-G21898

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

49.5 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human WDR77 / MEP50 Protein (Recombinant His, N-Terminal) - LS-G143942

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

36.7 kDa

Price:

50 µg/$419

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Human WDR77 / MEP50 Protein (Recombinant GST) (Full Length) - LS-G35148

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.36 kDa

Price:

10 µg/$479; 25 µg/$670

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Human WDR77 / MEP50 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87576

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.5 kDa

Price:

20 µg/$150

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WDR77 / MEP50 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110024

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.5 kDa

Price:

100 µg/$494

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