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VRL1 / TRPV2

transient receptor potential cation channel, subfamily V, member 2

Transient Receptor Potential Vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.

Gene Name: transient receptor potential cation channel, subfamily V, member 2
Family/Subfamily: Ion Channel , Calcium channel - TRP
Synonyms: TRPV2, GRC, OTRPC2, Osm-9-like TRP channel 2, VRL-1, VRL1, VRL
Target Sequences: NM_016113 NP_057197.2 Q9Y5S1

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
VRL1 / TRPV2 (3)
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Alzheimer's Disease (3)
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His-T7 (1)
Myc-DDK (Flag) (2)
Human (1)
Mouse (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
VRL1 / TRPV2 Protein - Recombinant  Transient\xa0Receptor\xa0Potential\xa0Cation\xa0Channel\xa0Subfamily\xa0V,\xa0Member\xa02\xa0(TRPV2) By SDS-PAGE
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E. coli
His-T7
32.9 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
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293T Cells
Myc-DDK (Flag)
85.8 kDa
20 µg/$150
VRL1 / TRPV2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
85.8 kDa
100 µg/$494
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).