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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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VIL1 / Villin

villin 1

Epithelial cell-specific Ca2+-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis. Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium. Appears to regulate cell death by maintaining mitochondrial integrity. Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair. Upon S.flexneri cell infection, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination.

Gene Name: villin 1
Synonyms: VIL1, D2S1471, Villin, Villin 1, Villin-1, VIL
Target Sequences: NM_007127 NP_009058.2 P09327

Filtered By: None
Target
VIL1 / Villin (38)
Reactivity
Human (38)
Mouse (18)
Rat (3)
Chimpanzee (3)
Horse (4)
Monkey (4)
Orangutan (3)
Pig (8)
Application
IHC (23)
IHC-Fr (4)
IHC-P (13)
WB (27)
Flo (2)
ELISA (4)
ICC (4)
IF (2)
IHC-Fx (4)
SDS-PAGE (4)
Host
rabbit (24)
mouse (14)
Isotype
IgG (17)
IgG1 (8)
IgG1,k (3)
IgG2b (1)
IgG2b,k (1)
Clonality
monoclonal mc (12)
polyclonal pc (22)
recombinant monoclonal rmc (4)
Clone
3B3 (1)
3E5G11 (1)
3G6 (1)
5E3B2 (1)
ABT-VIL (1)
CWWB1 (6)
rVIL1/1325 (2)
VIL1/2310R (2)
Format
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (2)
PE Conjugated (1)
Ready-to-Use (2)
Unconjugated (26)
Epitope
aa1-320 (10)
C-Terminus (5)
aa179-311 (4)
aa1-188 (1)
aa1-350 (1)
aa180-207 (1)
aa7-246 (1)
aa770-799 (1)
Publications
No (38)
Showing 1-25 of 38 results

VIL1 / Villin Antibody IHC-plus™ LS-B2581
Mouse Monoclonal (IgG1) to Human VIL1 / Villin
Human
IHC IHC-P
Unconjugated
50µl  $425.00
Anti-VIL1 / Villin antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-VIL1 / Villin antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

VIL1 / Villin Antibody (C-Terminus) LS-C76819
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Mouse, Human
ICC IF WB
Unconjugated
100µl 0.03mg/ml  $530.00

VIL1 / Villin Antibody (aa770-799) LS-C407669
Rabbit Polyclonal to Human VIL1 / Villin
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg 0.5mg/ml  $325.00
Villin antibody IHC-paraffin. IHC(P): Mouse Intestine Tissue.
Villin antibody IHC-paraffin. IHC(P): Rat Intestine Tissue.
Villin antibody IHC-paraffin. IHC(P): Mouse Intestine Tissue.
Villin antibody IHC-paraffin. IHC(P): Rat Intestine Tissue.

VIL1 / Villin Antibody (clone CWWB1) IHC-plus™ LS-B8547
Mouse Monoclonal [clone CWWB1] (IgG1) to Human VIL1 / Villin
Human
IHC IHC-P
Unconjugated
250µl  $505.00
Anti-Villin antibody IHC of human small intestine, epithelial membrane. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Anti-Villin antibody IHC of human small intestine, epithelial membrane. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.

VIL1 / Villin Antibody (clone 3E5G11) LS-C669195
Mouse Monoclonal [clone 3E5G11] (IgG1) to Human VIL1 / Villin
Human
ELISA Flo IF IHC WB
Unconjugated
0.1mg  $365.00

VIL1 / Villin Antibody (aa7-246) LS-C186115
Rabbit Polyclonal to Human VIL1 / Villin
Human
ICC IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $335.00
IHC of paraffin-embedded A549 xenograft using Villin antibody at 1:500 dilution.
Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa using Villin antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.
IHC of paraffin-embedded A549 xenograft using Villin antibody at 1:500 dilution.
Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa using Villin antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.

VIL1 / Villin Antibody (aa180-207) LS-C160527
Rabbit Polyclonal to Human VIL1 / Villin
Mouse, Human
Flo IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human colon carcinoma reacted with Villin-1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Villin-1 Antibody western blot of HT29 cell line and mouse kidney tissue lysates (35 ug/lane). The Villin-1 antibody detected the Villin-1 protein (arrow).
Formalin-fixed and paraffin-embedded human colon carcinoma reacted with Villin-1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Villin-1 Antibody western blot of HT29 cell line and mouse kidney tissue lysates (35 ug/lane). The Villin-1 antibody detected the Villin-1 protein (arrow).

VIL1 / Villin Antibody IHC-plus™ LS-B13880
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Mouse, Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

VIL1 / Villin Antibody (clone 5E3B2) LS-C669186
Mouse Monoclonal [clone 5E3B2] (IgG2b) to Human VIL1 / Villin
Human
ELISA IHC WB
Unconjugated
0.1mg  $365.00

VIL1 / Villin Antibody LS-C490133
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg  $365.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

VIL1 / Villin Antibody (clone ABT-VIL) LS-C744580
Mouse Monoclonal [clone ABT-VIL] (IgG) to Human VIL1 / Villin
Human
IHC WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Appendix
Colon 1
Appendix
Colon 1

VIL1 / Villin Antibody (clone CWWB1) LS-C202916
Mouse Monoclonal [clone CWWB1] (IgG1) to Human VIL1 / Villin
Human
IHC IHC-Fr IHC-P
Unconjugated
1ml  $875.00

VIL1 / Villin Antibody (clone CWWB1) LS-C312202
Mouse Monoclonal [clone CWWB1] (IgG1) to Human VIL1 / Villin
Human
IHC IHC-Fr IHC-P
Unconjugated
100µl 100µg/ml  $255.00; 500µl 100µg/ml  $375.00; 1000µl 100µg/ml  $495.00
IHC of Villin on FFPE Colon tissue.
IHC of Villin on FFPE Colon tissue.

VIL1 / Villin Antibody (clone CWWB1, Ready-to-Use) LS-C348624
Mouse Monoclonal [clone CWWB1] (IgG1) to Human VIL1 / Villin
Human
IHC IHC-Fr IHC-P
Unconjugated, Ready-to-Use
3000µl  $235.00; 7000µl  $285.00; 15000µl  $385.00
IHC of Villin on FFPE Colon tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.
IHC of Villin on FFPE Colon tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.

VIL1 / Villin Antibody (aa1-350) LS-C376994
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Human
ELISA IHC IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human rectal cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human rectal cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.

VIL1 / Villin Antibody LS-C341640
Rabbit Polyclonal to Human VIL1 / Villin
Mouse, Rat, Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00

VIL1 / Villin Antibody (aa1-320) LS-C314923
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Mouse, Pig, Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of recombinant VIL1 / Villin.
Western blot of recombinant VIL1 / Villin.

VIL1 / Villin Antibody (aa1-320, HRP) LS-C711703
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Mouse, Pig, Human
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $345.00; 1ml  $680.00; 10ml  $2,730.00
Western blot of recombinant VIL1 / Villin.
Western blot of recombinant VIL1 / Villin.

VIL1 / Villin Antibody (aa1-320, Biotin) LS-C422419
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Human
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00

VIL1 / Villin Antibody (aa1-320, Biotin) LS-C687276
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Mouse, Pig, Human
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,310.00
Western blot of recombinant VIL1 / Villin.
Western blot of recombinant VIL1 / Villin.

VIL1 / Villin Antibody (aa1-320, FITC) LS-C422418
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Human
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

VIL1 / Villin Antibody (aa1-320, FITC) LS-C694088
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Mouse, Pig, Human
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of recombinant VIL1 / Villin.
Western blot of recombinant VIL1 / Villin.

VIL1 / Villin Antibody (aa1-320, Cy3) LS-C702680
Rabbit Polyclonal (IgG) to Human VIL1 / Villin
Mouse, Pig, Human
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $445.00; 1ml  $1,050.00; 10ml  $4,200.00
Western blot of recombinant VIL1 / Villin.
Western blot of recombinant VIL1 / Villin.

VIL1 / Villin Antibody (clone CWWB1, Ready-to-Use) LS-C756767
Mouse Monoclonal [clone CWWB1] (IgG1) to Human VIL1 / Villin
Human
IHC-Fr IHC-P WB
Unconjugated, Ready-to-Use
7ml  $530.00

VIL1 / Villin Antibody (clone CWWB1) LS-C756777
Mouse Monoclonal [clone CWWB1] (IgG1,k) to Human VIL1 / Villin
Human
IHC-P WB
Unconjugated
1ml  $725.00
Showing 1-25 of 38 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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