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VEGFC

vascular endothelial growth factor C

Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Gene Name: vascular endothelial growth factor C
Family/Subfamily: PDGF , not assigned-PDGF
Synonyms: VEGFC, Flt4-L, FLT4 ligand DHM, VEGF-C, VRP, Flt4 ligand
Target Sequences: NM_005429 NP_005420.1 P49767

Publications (2)

1
MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer. Hirata H, Hinoda Y, Ueno K, Shahryari V, Tabatabai ZL, Dahiya R. Carcinogenesis. 2012 33:41-8. [PubMed:22049531] [PMC:PMC3276333]
2
Peripheral Nerve Single-Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth. Jeremy S Toma, Konstantina Karamboulas, Matthew J Carr, Adelaida Kolaj, Scott A Yuzwa, Neemat Mahmud, Mekayla A Storer, David R Kaplan, Freda D Miller. eNeuro. 2020 May;7: [Full Text Article] [PubMed:32349983] [PMC:PMC7294463]

☰ Filters
Products
Proteins (25)
Over-Expression Lysate (2)
Recombinant (23)
VEGFC (25)
No (25)
6His, C-terminus (1)
6His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His (5)
His, N-Terminal (1)
His,C-terminus (1)
His-GST (1)
His-S (3)
His-T7 (1)
Myc-DDK (Flag) (2)
Bovine (1)
Chicken (1)
Dog (1)
Human (14)
Mouse (4)
Rabbit (1)
Rat (2)
293T Cells (1)
CHO Cells (1)
E. coli (14)
HEK 293 Cells (4)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (7)
Low endotoxin level (10)
Biologically active (5)
VEGFC Protein - Recombinant  Vascular Endothelial Growth Factor C By SDS-PAGE
Select
E. coli
His-GST
43.1 kDa
10 µg/$279; 50 µg/$470; 100 µg/$750; 200 µg/$936; 1 mg/$2,046
VEGFC Protein
Select
HEK 293 Cells
His
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
15 kDa. DTT-reduced protein migrates as 18-23 kDa due to glycosylation
10 µg/$466
VEGFC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.7 kDa
20 µg/$130
VEGFC Protein
Select
Yeast
His
15 kD
500 µg/$1,080; 100 µg/$489; 20 µg/$354
VEGFC Protein - Recombinant  Vascular Endothelial Growth Factor C By SDS-PAGE
Select
E. coli
His-S
16.8 kDa
10 µg/$279; 50 µg/$470; 100 µg/$750; 200 µg/$936; 1 mg/$2,046
VEGFC Protein - Recombinant  Vascular Endothelial Growth Factor C By SDS-PAGE
Select
E. coli
His-S
16.8 kDa
10 µg/$284; 50 µg/$498; 100 µg/$796; 200 µg/$993; 1 mg/$2,145
VEGFC Protein - Recombinant  Vascular Endothelial Growth Factor C By SDS-PAGE
Select
E. coli
His-S
16.8 kDa
10 µg/$281; 50 µg/$479; 100 µg/$765; 200 µg/$955; 1 mg/$2,079
VEGFC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.7 kDa
100 µg/$458
VEGFC Protein - Active Vascular Endothelial Growth Factor C (VEGFC) by WB
Select
E. coli
His, N-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
45kDa
10 µg/$285; 50 µg/$505; 200 µg/$1,005; 100 µg/$808; 1 mg/$2,172
Select
HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
13.5 kDa
20 µg/$325; 5 µg/$252
Select
E. coli
His
17.1 kD
1 mg/$1,646; 100 µg/$490; 20 µg/$354
Select
E. coli
GST
40.5 kD
1 mg/$1,152; 100 µg/$400; 20 µg/$307
VEGFC Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$461; 25 µg/$611
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein.
15-16 kDa
50 µg/$687; 1 mg/$3,422; 10 µg/$376
Select
E. coli
None
Less than 0.1 ng/µg of protein.
15.0 kDa
50 µg/$825; 1 mg/$4,562; 10 µg/$376
Select
E. coli
None
Less than 0.1 ng/µg of protein.
15.0 kDa
50 µg/$825; 1 mg/$4,562; 10 µg/$385
VEGFC Protein - HUVEC cell proliferation induced by human VEGF-C.
Select
CHO Cells
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 135 amino acid recombinant protein has a predicted molecular mass of approximately 15.4 kD. The DTT-reduced and non-reduced protein migrate at approximately 23-28 and 20-25 kD by SDS-PAGE respectively. The N-terminal amino acid is Thr.
10 µg/$282; 25 µg/$340; 100 µg/$587
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.3 kDa
10 µg/$287; 50 µg/$450
Select
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16~19 kDa (SDS-PAGE)
50 µg/$336; 10 µg/$252; 1 mg/$1,531
VEGFC Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
15.4 kDa
10 µg/$255; 50 µg/$305; 100 µg/$355; 200 µg/$474
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.27kD
10 µg/$282; 50 µg/$446; 500 µg/$1,439; 1 mg/$2,055
VEGFC Protein - Recombinant Vascular Endothelial Growth Factor C By SDS-PAGE
Select
E. coli
His
14.5 kDa
10 µg/$268; 50 µg/$403; 100 µg/$643; 200 µg/$803; 1 mg/$1,814
VEGFC Protein - Recombinant Vascular Endothelial Growth Factor C By SDS-PAGE
Select
E. coli
His-T7
45.5 kDa
10 µg/$267; 50 µg/$393; 100 µg/$627; 200 µg/$784; 1 mg/$1,781
VEGFC Protein - Recombinant Vascular Endothelial Growth Factor C By SDS-PAGE
Select
E. coli
His
14.6 kDa
10 µg/$278; 50 µg/$460; 100 µg/$734; 200 µg/$917; 1 mg/$2,013
VEGFC Protein - 12.5% SDS-PAGE of human VEGFC stained with Coomassie Blue
Select
Wheat Germ Extract
GST
71.72 kDa
2 µg/$421
Viewing 1-25 of 25 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).