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VEGFC
vascular endothelial growth factor C
Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
| Gene Name: | vascular endothelial growth factor C |
| Family/Subfamily: | PDGF , not assigned-PDGF |
| Synonyms: | VEGFC, Flt4-L, FLT4 ligand DHM, VEGF-C, VRP, Flt4 ligand |
| Target Sequences: | NM_005429 NP_005420.1 P49767 |
Publications (2)
1
MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer. Hirata H, Hinoda Y, Ueno K, Shahryari V, Tabatabai ZL, Dahiya R. Carcinogenesis. 2012 33:41-8.
[PubMed:22049531]
[PMC:PMC3276333]
2
Peripheral Nerve Single-Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth. Jeremy S Toma, Konstantina Karamboulas, Matthew J Carr, Adelaida Kolaj, Scott A Yuzwa, Neemat Mahmud, Mekayla A Storer, David R Kaplan, Freda D Miller. eNeuro. 2020 May;7: [Full Text Article]
[PubMed:32349983]
[PMC:PMC7294463]
☰ Filters
Products
Proteins
(21)
Type
Over-Expression Lysate
(2)
Recombinant
(19)
Target
VEGFC
(21)
Publications
No
(21)
Tag
6His, C-terminus
(1)
6His, N-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His
(4)
His, N-Terminal
(1)
His,C-terminus
(1)
His-GST
(1)
His-S
(3)
His-T7
(1)
Myc-DDK (Flag)
(2)
Species
Bovine
(1)
Chicken
(1)
Dog
(1)
Human
(12)
Mouse
(3)
Rabbit
(1)
Rat
(1)
Source
293T Cells
(1)
CHO Cells
(1)
E. coli
(11)
HEK 293 Cells
(3)
Human Cells
(1)
Mammalian Cells
(1)
Wheat Germ Extract
(2)
Yeast
(1)
Purification
Purified
(3)
Low Endotoxin Level
Low endotoxin level
(5)
Biologically Active
Biologically active
(3)
E. coli
His-GST
43.1 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
13.5 kDa
20 µg/$349; 5 µg/$268
CHO Cells
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 135 amino acid recombinant protein has a predicted molecular mass of approximately 15.4 kD. The DTT-reduced and non-reduced protein migrate at approximately 23-28 and 20-25 kD by SDS-PAGE respectively. The N-terminal amino acid is Thr.
10 µg/$306; 25 µg/$375; 100 µg/$731
E. coli
His, N-Terminal
45kDa
10 µg/$295; 50 µg/$530; 200 µg/$1,045; 100 µg/$847; 1 mg/$2,211; 500 µg/$1,728; 5 mg/$3,697; 2 mg/$2,402
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST
71.72 kDa
2 µg/$439
Yeast
His
15 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
E. coli
His-S
16.8 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
E. coli
His-S
16.8 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
E. coli
His-S
16.8 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
E. coli
GST
40.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
E. coli
His
17.1 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
293T Cells
Myc-DDK (Flag)
46.7 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
46.7 kDa
100 µg/$494
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.3 kDa
10 µg/$297; 50 µg/$460
E. coli
6His, N-terminus
15.4 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 200 µg/$484
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16~19 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$273; 1 mg/$1,740
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.27kD
10 µg/$297; 50 µg/$468; 500 µg/$1,585; 1 mg/$2,157
E. coli
His-T7
45.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
E. coli
His
14.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His
14.6 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
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