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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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VCAM1 / CD106
vascular cell adhesion molecule 1
Vascular cell adhesion molecule 1, VCAM-1, is a surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of monocytes and lymphocytes. VCAM-1 and integrin alpha-4-beta-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization. Studies of heart development have shown that deficiencies of VCAM and in alpha-4 integrin also result in epicardial dissolution and subsequent myocardial thinning.
| Gene Name: | vascular cell adhesion molecule 1 |
| Family/Subfamily: | ICAM , not assigned-ICAM |
| Synonyms: | VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1 |
| Target Sequences: | NM_001078 NP_001069.1 P19320 |
Publications (2)
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