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VCAM1 / CD106

vascular cell adhesion molecule 1

Vascular cell adhesion molecule 1, VCAM-1, is a surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of monocytes and lymphocytes. VCAM-1 and integrin alpha-4-beta-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization. Studies of heart development have shown that deficiencies of VCAM and in alpha-4 integrin also result in epicardial dissolution and subsequent myocardial thinning.

Gene Name: vascular cell adhesion molecule 1
Family/Subfamily: ICAM , not assigned-ICAM
Synonyms: VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1
Target Sequences: NM_001078 NP_001069.1 P19320

Publications (2)

1
Renal denervation and CD161a immune ablation prevent cholinergic hypertension and renal sodium retention. Nandita Raikwar, Cameron Braverman, Peter M Snyder, Robert A Fenton, David K Meyerholz, Francois M Abboud, Sailesh C Harwani. American journal of physiology. Heart and circulatory physiology. 2019 September;317:H517-H530. [Full Text Article] [PubMed:31172810] [PMC:PMC6766722]
2
SPARC Production by Bone Marrow-Derived Cells Contributes to Myocardial Fibrosis in Pressure-Overload. Hannah J Riley, Ryan R Kelly, An O Van Laer, Lily S Neff, Shaoni Dasgupta, Catalin F Baicu, Lindsay T McDonald, Amanda C LaRue, Michael R Zile, Amy D Bradshaw. American journal of physiology. Heart and circulatory physiology. 2020 December; [Full Text Article] [PubMed:33306449] Related Antibodies: LS-C661877.

☰ Filters
Products
Proteins (27)
Over-Expression Lysate (2)
Recombinant (25)
VCAM1 / CD106 (27)
No (27)
6His, C-terminus (2)
6His, N-terminus (2)
Fc (1)
Fc, C-terminus (1)
GST (1)
GST, N-terminus (1)
His (5)
His-Fc (1)
His-S (1)
His-SUMO (1)
His-T7 (3)
Myc-DDK (Flag) (4)
Dog (1)
Human (14)
Mouse (7)
Rabbit (1)
Rat (2)
Rhesus monkey (1)
293T Cells (1)
CHO Cells (1)
E. coli (10)
HEK 293 Cells (5)
Human (1)
Human Cells (4)
Mammalian Cells (2)
Wheat Germ Extract (2)
Yeast (1)
Purified (7)
Low endotoxin level (10)
Biologically active (3)
VCAM1 / CD106 Protein
Select
E. coli
6His, N-terminus
77.4 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
VCAM1 / CD106 Protein - Purified recombinant protein VCAM1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
78.7 kDa
20 µg/$1,107
Select
Human
None
Less than 1.0 EU/µg protein (determined by LAL method).
101.4kD
50 µg/$395; 500 µg/$1,262; 1 mg/$1,627; 10 µg/$277
VCAM1 / CD106 Protein - Recombinant Vascular Cell Adhesion Molecule 1 By SDS-PAGE
Select
E. coli
His-T7
29.9 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
CHO Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
74.4 kDa
10 µg/$268; 50 µg/$349
VCAM1 / CD106 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
101.4 kDa
10 µg/$277; 50 µg/$389
VCAM1 / CD106 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
81.28 kDa
100 µg/$494
VCAM1 / CD106 Protein - 12.5% SDS-PAGE of human VCAM1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
106.81 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
His-SUMO
90.2 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
VCAM1 / CD106 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
VCAM1 / CD106 Protein - Purified recombinant protein VCAM1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
68.7 kDa
20 µg/$1,107
VCAM1 / CD106 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
81.28 kDa
20 µg/$150
Select
Human Cells
His-Fc
Less than 1.0 EU/µg protein (determined by LAL method).
102 kDa
100 µg/$502
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
75.8 kDa
100 µg/$661; 1 mg/$3,499
VCAM1 / CD106 Protein
Select
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Select
HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
74.0 kDa
10 µg/$268; 50 µg/$349
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
75.3 kDa
10 µg/$248; 50 µg/$317
Select
HEK 293 Cells
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 914 amino acid recombinant protein with a C-terminal human IgG1 Fc tag has a predicted molecular mass of approximately 101.4 kD. The protein migrates at approximately 130 kD by SDS-PAGE in DTT-reducing conditions and approximately 260 kD in non-reduci
25 µg/$306; 100 µg/$436
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
75.26kD
10 µg/$248; 50 µg/$321; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
101 kDa
100 µg/$502
VCAM1 / CD106 Protein - Recombinant Vascular Cell Adhesion Molecule 1 By SDS-PAGE
Select
E. coli
His
24.8 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
VCAM1 / CD106 Protein - Recombinant Vascular Cell Adhesion Molecule 1 By SDS-PAGE
Select
E. coli
His-T7
35.8 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
VCAM1 / CD106 Protein - Recombinant Vascular Cell Adhesion Molecule 1 By SDS-PAGE
Select
E. coli
His
20.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
VCAM1 / CD106 Protein - Recombinant Vascular Cell Adhesion Molecule 1 By SDS-PAGE
Select
E. coli
His-T7
13.2 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
Viewing 1-25 of 27 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).