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UTRN / Utrophin

Utrophin

The utrophin protein accumulates at neuromuscular synapses and myotendinous junctions. Similarly to dystrophin, utrophin associates with the sarcolemmal dystroglycan complex and anchors the cytoskeleton protein to agrin and laminin in the plasma membrane. Duchenne Muscular Dystrophy (DMD), a disease caused by mutations of the dystrophin gene, is a severe progressive muscle-degenerative disorder that results in premature death. Because utrophin is up-regulated and can compensate for the absence of functional dystrophin in the mouse model for DMD, this gene may prove a useful therapeutic alternative in the treatment of the disease.

Gene Name: Utrophin
Synonyms: UTRN
Target Sequences: NM_007124 NP_009055.2 P46939

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Proteins (2)
Recombinant (2)
UTRN / Utrophin (2)
No (2)
GST, N-terminus (1)
His, N-Terminal (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
UTRN / Utrophin Protein - Recombinant  Utrophin By SDS-PAGE
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E. coli
His, N-Terminal
32.5 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
UTRN / Utrophin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).