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Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
Gene Name: | Ubiquitin Specific Peptidase 46 |
Synonyms: | USP46, Deubiquitinating enzyme 46, Ubiquitin specific protease 46, Ubiquitin thioesterase 46, Ubiquitin thiolesterase 46 |
Target Sequences: | NM_022832 NP_073743.2 P62068 |
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