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USP46

Ubiquitin Specific Peptidase 46

Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.

Gene Name:	Ubiquitin Specific Peptidase 46
Synonyms:	USP46, Deubiquitinating enzyme 46, Ubiquitin specific protease 46, Ubiquitin thioesterase 46, Ubiquitin thiolesterase 46
Target Sequences:	NM_022832 NP_073743.2 P62068

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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