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USP36
ubiquitin specific peptidase 36
May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
| Gene Name: | ubiquitin specific peptidase 36 |
| Family/Subfamily: | Protease , Cysteine C19 |
| Synonyms: | USP36, DUB1, Deubiquitinating enzyme 1, KIAA1453, Ubiquitin thioesterase 36, Ubiquitin specific protease 36, Deubiquitinating enzyme 36, Ubiquitin thiolesterase 36 |
| Target Sequences: | NM_025090 NP_079366.3 Q9P275 |
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