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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Gene Name: ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Family/Subfamily: Protease , Cysteine C19
Synonyms: USP14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin thiolesterase 14, TGT, TRNA-guanine transglycosylase, Ubiquitin specific protease 14
Target Sequences: NM_005151 NP_005142.1 P54578

Filtered by: None
Target
USP14 (39)
Reactivity
Human (38)
Mouse (6)
Rat (3)
Rabbit (1)
Application
IHC (11)
IHC-P (3)
WB (38)
Flo (1)
ELISA (24)
IF (1)
IP (2)
Host
rabbit (35)
mouse (2)
goat (1)
chicken (1)
Isotype
IgG (22)
IgG1 (1)
IgG2a,k (1)
IgY (1)
Clonality
monoclonal mc (2)
polyclonal pc (37)
Clone
1F8 (1)
889CT6.2.1 (1)
Format
AP Conjugated (2)
APC (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (17)
Epitope
aa1-30 (8)
aa1-494 (8)
aa355-383 (8)
C-Terminus (2)
aa350-400 (1)
aa450-C-term (1)
Publications
No (39)
Showing 1-25 of 39 results

IHC-plus™ USP14 Antibody (aa450-C-term) LS-B13991
Rabbit Polyclonal (IgG) to Human USP14
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

USP14 Antibody LS-C661483
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, Flo, IF, WB
Unconjugated
100µg  $435.00

USP14 Antibody (aa1-30) LS-C99554
Rabbit Polyclonal to Human USP14
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
The anti-USP14 antibody is used in Western blot to detect USP14 in USP14-transfected HeLa cell lysates. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland).

USP14 Antibody (aa350-400) LS-C287760
Rabbit Polyclonal (IgG) to Human USP14
Human
IHC, IHC-P, IP, WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human USP14 by Immunohistochemistry : Formalin-Fixed, Paraffin-Embedded (FFPE)
Detection of Human USP14 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T(50 ug) cells. Antibodies: Affinity purified rabbit anti-USP14 antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

USP14 Antibody (clone 1F8) LS-C139458
Mouse Monoclonal [clone 1F8] (IgG2a,k) to Human USP14
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg  $365.00
USP14 monoclonal antibody (M08), clone 1F8. Western blot of USP14 expression in PC-12.
USP14 monoclonal antibody (M08), clone 1F8. Western blot of USP14 expression in HeLa NE.

USP14 Antibody (aa1-30) LS-C329058
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

USP14 Antibody (aa1-30, Biotin) LS-C284173
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

USP14 Antibody (aa1-30, FITC) LS-C284174
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

USP14 Antibody (aa1-30, APC) LS-C284171
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

USP14 Antibody (aa1-30, PE) LS-C284176
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

USP14 Antibody (aa1-30, AP) LS-C284172
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

USP14 Antibody (aa1-30, Azide-free, HRP) LS-C284175
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

USP14 Antibody LS-C317696
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human kidney tissue using USP14 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostate cancer using USP14 Antibody at dilution of 1:100

USP14 Antibody (Biotin) LS-C317693
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00
Western blot of Ubiquitin carboxyl-terminal hydrolase 14 antibody at 2 ug/ml lane 1: HeLa whole cell lysate lane 2: 293T whole cell lysate Lane 3: NIH3T3 whole cell lysate Secondary: Goat polyclonal to Rabbit IgG at 1:10000 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

USP14 Antibody (C-Terminus) LS-C348853
Rabbit Polyclonal to Human USP14
Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $255.00
Immunohistochemistry of USP14 antibody
Western blot of USP14 antibody

USP14 Antibody (C-Terminus) LS-C47055
Rabbit Polyclonal to Human USP14
Rabbit, Mouse, Human
ELISA, WB
Unconjugated
100µg  $305.00

USP14 Antibody (aa355-383) LS-C326226
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
Unconjugated
200µl  $590.00

USP14 Antibody (aa355-383, Biotin) LS-C273164
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

USP14 Antibody (aa355-383, FITC) LS-C273166
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

USP14 Antibody (aa355-383, AP) LS-C273163
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
AP Conjugated
200µl  $740.00

USP14 Antibody (aa355-383, Azide-free, HRP) LS-C273167
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

USP14 Antibody (aa355-383, PE) LS-C273168
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
PE Conjugated
200µl  $740.00

USP14 Antibody (aa355-383, APC) LS-C273165
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
APC Conjugated
200µl  $740.00

USP14 Antibody LS-C778410
Rabbit Polyclonal to Human USP14
Mouse, Human
ELISA, WB
Unconjugated
100µg 100µl 1mg/ml  $305.00

USP14 Antibody LS-C808394
Rabbit Polyclonal (IgG) to Human USP14
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image
Showing 1-25 of 39 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).