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USF1 / USF
upstream transcription factor 1
USF1 / USF is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21.
| Gene Name: | upstream transcription factor 1 |
| Synonyms: | USF1, BHLHb11, FCHL, FCHL1, MLTFI, USF, UEF, HYPLIP1, MLTF, Upstream stimulatory factor 1 |
| Target Sequences: | NM_007122 NP_009053.1 P22415 |
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