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US01 / p115
USO1 vesicle transport factor
US01 / p115 is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants.
| Gene Name: | USO1 vesicle transport factor |
| Synonyms: | USO1, p115, Protein USO1 homolog, TAP, Vesicle docking protein p115, Vesicle-docking protein, US01, USO1 vesicle transport factor, VDP |
| Target Sequences: | NM_003715 NP_003706.2 O60763 |
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