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UROD is an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
Gene Name: | uroporphyrinogen decarboxylase |
Synonyms: | UROD, URO-D, Uroporphyrinogen decarboxylase, PCT, UPD |
Target Sequences: | NM_000374 NP_000365.3 P06132 |
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