URM1

ubiquitin related modifier 1

Acts as a sulfur carrier required for 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm5S2U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

URM1 (4)

Publications

No (4)

Tag

His (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

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URM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109357

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.2 kDa

Price:

100 µg/$494

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Human URM1 Protein (Recombinant His) - LS-G1214

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human URM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87070

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.2 kDa

Price:

20 µg/$150

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Human URM1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70428

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.2 kDa

Price:

20 µg/$1,107

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