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ULBP1

UL16 binding protein 1

Ligand for the KLRK1/NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.

Gene Name: UL16 binding protein 1
Synonyms: ULBP1, Alcan-beta, N2DL1, NKG2DL1, NKG2D ligand 1, RAET1I, N2DL-1, UL16 binding protein 1, UL16-binding protein 1
Target Sequences: NM_025218 NP_079494.1 Q9BZM6

☰ Filters
Products
Proteins (10)
Recombinant (10)
ULBP1 (10)
No (10)
6His, C-terminus (4)
Fc, C-terminus (2)
GST (1)
His (1)
His,C-terminus (1)
His-Fc (1)
Human (8)
Mouse (2)
E. coli (1)
HEK 293 Cells (1)
Human Cells (4)
Mammalian Cells (3)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (8)
ULBP1 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.8 kDa
100 µg/$721
ULBP1 Protein - 12.5% SDS-PAGE of human ULBP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
54.4 kDa
10 µg/$479; 25 µg/$670
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
22.3 kDa
10 µg/$277; 50 µg/$389
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.3 kDa
10 µg/$281; 50 µg/$389
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.4 kDa
10 µg/$281; 50 µg/$389
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.4kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.3kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
22.3kD
10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627
Select
Human Cells
His-Fc
Less than 1.0 EU/µg protein (determined by LAL method).
50.4 kDa
100 µg/$721
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).