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UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4-methylumbelliferone > dihydrotestosterone (DHT) > androstane-3-alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT).
Gene Name: | UDP glucuronosyltransferase 2 family, polypeptide B17 |
Synonyms: | UGT2B17, C19-steroid-specific UDPGT, UDPGT 2B17, UDPGT2B17 |
Target Sequences: | NM_001077 NP_001068.1 O75795 |
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