UGT1A3

UDP glucuronosyltransferase 1 family, polypeptide A3

UGT1A3 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

UGT1A3 (4)

Publications

No (4)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human UGT1A3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87978

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.3 kDa

Price:

20 µg/$215

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UGT1A3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111434

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.3 kDa

Price:

100 µg/$710

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Human UGT1A3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70780

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.3 kDa

Price:

20 µg/$1,107

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Human UGT1A3 Protein (Recombinant GST, N-terminus) (aa30-129) - LS-G62607

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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