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UCP1 / UCP-1

uncoupling protein 1 (mitochondrial, proton carrier)

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Gene Name: uncoupling protein 1 (mitochondrial, proton carrier)
Family/Subfamily: Transporter , Mitochondrial carrier
Synonyms: UCP1, Thermogenin, SLC25A7, UCP-1, UCP 1
Target Sequences: NM_021833 NP_068605.1 P25874

☰ Filters
Antibodies (50)
ELISA Kits (14)
Proteins (8)
Custom (4)
Over-Expression Lysate (2)
Primary (50)
Recombinant (6)
Sandwich (9)
Sandwich CLIA (1)
UCP1 / UCP-1 (72)
Human (30)
Mouse (24)
Rat (26)
Bovine (3)
Dog (1)
Gibbon (3)
Sheep (3)
IHC (7)
IHC-P (3)
WB (47)
ELISA (14)
ICC (1)
IF (1)
Peptide-ELISA (2)
rabbit (47)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
IgG (15)
IgG2a,k (1)
IgG2b (1)
monoclonal mc (2)
polyclonal pc (48)
4B7 (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (3)
96-Well Strip Plate (9)
APC (3)
APC Conjugated (3)
Biotin Conjugated (5)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (5)
HRP Conjugated (6)
PE Conjugated (3)
Preservative Free (1)
Unconjugated (22)
aa179-296 (22)
C-Terminus (7)
aa77-126 (4)
aa1-307 (2)
aa290-301 (1)
No (72)
Cell Culture Supernatants (1)
Cell Lysates (3)
Plasma (7)
Serum (7)
Tissue Homogenates (4)
GST, N-terminus (1)
His (3)
His-GST (1)
His-SUMO (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (1)
Rat (2)
293T Cells (1)
E. coli (4)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Yeast (1)
UCP1 / UCP-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
UCP1 / UCP-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
UCP1 / UCP-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
UCP1 / UCP-1 Antibody - Anti-UCP1 / UCP-1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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UCP1 / UCP-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
UCP1 / UCP-1 Antibody - Antibody (1 ug/ml) staining of Human Adipose lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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UCP1 / UCP-1 Goat anti-Human Polyclonal (aa290-301) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
UCP1 / UCP-1 Antibody
Select
UCP1 / UCP-1 Rabbit anti-Mouse Polyclonal (aa179-296) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
UCP1 / UCP-1 Antibody - UCP1 antibody Western blot of A549 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCP1 / UCP-1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
UCP1 / UCP-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$783
UCP1 / UCP-1 Antibody - Immunofluorescence staining of UCP2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human UCP2 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
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UCP1 / UCP-1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF
Unconjugated, Preservative Free
100 µl/$412
Select
UCP1 / UCP-1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µl/$801
Select
UCP1 / UCP-1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µl/$801
UCP1 / UCP-1 Antibody - UCP1 monoclonal antibody (M03), clone 4B7. Western blot of UCP1 expression in NIH/3T3.
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UCP1 / UCP-1 Mouse anti-Human Monoclonal (4B7) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$423
UCP1 / UCP-1 Antibody - Immunohistochemistry of paraffin-embedded human testis using antibody at 1:100 dilution.
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UCP1 / UCP-1 Rabbit anti-Human Polyclonal (aa1-307) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
UCP1 / UCP-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
UCP1 / UCP-1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Select
UCP1 / UCP-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
UCP1 / UCP-1 Antibody - Immunohistochemistry of paraffin-embedded human testis using antibody at 1:100 dilution.
Select
UCP1 / UCP-1 Rabbit anti-Human Polyclonal (aa1-307) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
UCP1 / UCP-1 Antibody - 1:100 staining mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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UCP1 / UCP-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
UCP1 / UCP-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
UCP1 / UCP-1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µg/$832
UCP1 / UCP-1 Antibody - Western blot analysis of extracts of various cell lines, using UCP1 antibody.
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UCP1 / UCP-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
UCP1 / UCP-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
UCP1 / UCP-1 Antibody - IHC image of UCP1 Antibody diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
UCP1 / UCP-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
UCP1 / UCP-1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
UCP1 / UCP-1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 72 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).