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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UCP1 / UCP-1

uncoupling protein 1 (mitochondrial, proton carrier)

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Gene Name: uncoupling protein 1 (mitochondrial, proton carrier)
Family/Subfamily: Transporter , Mitochondrial carrier
Synonyms: UCP1, Thermogenin, SLC25A7, UCP-1, UCP 1
Target Sequences: NM_021833 NP_068605.1 P25874

Filtered By: None
Target
UCP1 / UCP-1 (53)
Reactivity
Human (25)
Mouse (22)
Rat (24)
Bovine (4)
Gibbon (3)
Monkey (1)
Sheep (4)
Application
IHC (27)
IHC-P (3)
WB (52)
ELISA (12)
Peptide-ELISA (1)
Host
rabbit (50)
mouse (2)
goat (1)
Isotype
IgG (35)
IgG2a,k (1)
IgG2b (1)
Clonality
monoclonal mc (2)
polyclonal pc (51)
Clone
4B7 (1)
Format
APC (3)
APC Conjugated (3)
Biotin Conjugated (5)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (24)
Epitope
aa179-296 (23)
C-Terminus (8)
aa77-126 (4)
aa1-307 (2)
aa289-307 (2)
aa274-302 (1)
aa290-301 (1)
Publications
No (53)
Showing 1-25 of 53 results

UCP1 / UCP-1 Antibody (C-Terminus) IHC-plus™ LS-B10185
Rabbit Polyclonal (IgG) to Human UCP1 / UCP-1
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-UCP1 / UCP-1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot analysis of UCP1 in HeLa cell lysate with UCP1 antibody at 1 ug/ml.
Anti-UCP1 / UCP-1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot analysis of UCP1 in HeLa cell lysate with UCP1 antibody at 1 ug/ml.

UCP1 / UCP-1 Antibody (aa290-301) LS-C55645
Goat Polyclonal to Human UCP1 / UCP-1
Human
Peptide-ELISA WB
Unconjugated
100µg 0.5mg/ml  $405.00
Antibody (1 ug/ml) staining of Human Adipose lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (1 ug/ml) staining of Human Adipose lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

UCP1 / UCP-1 Antibody (C-Terminus) LS-C146466
Rabbit Polyclonal to Human UCP1 / UCP-1
Mouse, Sheep, Bovine, Rat, Human
WB
Unconjugated
50µg  $365.00
UCP1 antibody Western blot of A549 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UCP1 antibody Western blot of A549 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UCP1 / UCP-1 Antibody (C-Terminus) LS-C10944
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse, Rat
ELISA WB
Unconjugated
50µl  $435.00; 100µl  $725.00

UCP1 / UCP-1 Antibody (C-Terminus) LS-C10945
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse, Rat
ELISA WB
Unconjugated
50µl  $435.00; 100µl  $725.00

UCP1 / UCP-1 Antibody LS-C317904
Rabbit Polyclonal (IgG) to Human UCP1 / UCP-1
Human
ELISA WB
Unconjugated
50µg  $285.00; 100µg  $385.00

UCP1 / UCP-1 Antibody (HRP) LS-C317903
Rabbit Polyclonal (IgG) to Human UCP1 / UCP-1
Human
ELISA WB
HRP Conjugated
50µg  $285.00; 100µg 0.34mg/ml  $385.00

UCP1 / UCP-1 Antibody LS-C87137
Rabbit Polyclonal to Mouse UCP1 / UCP-1
Mouse
WB
Unconjugated
100µg 1mg/ml  $710.00

UCP1 / UCP-1 Antibody (aa274-302) LS-C157015
Rabbit Polyclonal to Human UCP1 / UCP-1
Mouse, Human
WB
Unconjugated
50µg 0.25mg/ml  $250.00
UCP1 Antibody (C-term) Western blot analysis in 293 cell line lysates (35 ug/lane). This demonstrates the UCP1 antibody detected the UCP1 protein (arrow).
UCP1 Antibody (C-term) Western blot analysis in mouse heart tissue lysates (35 ug/lane). This demonstrates the UCP1 antibody detected the UCP1 protein (arrow).
UCP1 Antibody (C-term) Western blot analysis in 293 cell line lysates (35 ug/lane). This demonstrates the UCP1 antibody detected the UCP1 protein (arrow).
UCP1 Antibody (C-term) Western blot analysis in mouse heart tissue lysates (35 ug/lane). This demonstrates the UCP1 antibody detected the UCP1 protein (arrow).

UCP1 / UCP-1 Antibody (aa1-307) LS-C376978
Rabbit Polyclonal (IgG) to Human UCP1 / UCP-1
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human testis using antibody at 1:100 dilution.
Western blot. All lanes: Mitochondrial brown fat uncoupling protein 1 antibody at 2 ug/ml+mouse kidney tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 33 kDa. Observed band size: 33 kDa Immunohistochemistry.
Immunohistochemistry of paraffin-embedded human testis using antibody at 1:100 dilution.
Western blot. All lanes: Mitochondrial brown fat uncoupling protein 1 antibody at 2 ug/ml+mouse kidney tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 33 kDa. Observed band size: 33 kDa Immunohistochemistry.

UCP1 / UCP-1 Antibody LS-C661421
Rabbit Polyclonal (IgG) to Human UCP1 / UCP-1
Human
ELISA IHC WB
Unconjugated
100µg  $435.00

UCP1 / UCP-1 Antibody (aa179-296) LS-C296914
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00; 10ml 0.5mg/ml  $2,160.00

UCP1 / UCP-1 Antibody (aa179-296, HRP) LS-C713423
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $345.00; 1ml  $695.00; 10ml  $2,805.00

UCP1 / UCP-1 Antibody (aa179-296, Biotin) LS-C298483
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse
IHC WB
Biotin Conjugated
100µl 0.5mg/ml  $435.00

UCP1 / UCP-1 Antibody (aa179-296, FITC) LS-C301845
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse
IHC WB
FITC Conjugated
100µl 0.5mg/ml  $465.00

UCP1 / UCP-1 Antibody (aa179-296, APC, Cy7) LS-C736401
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse
IHC WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $465.00; 200µl  $650.00; 1ml  $1,620.00; 10ml  $6,480.00

UCP1 / UCP-1 Antibody (aa179-296, PE) LS-C727485
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00

UCP1 / UCP-1 Antibody (aa179-296, APC) LS-C741525
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $315.00; 200µl  $375.00; 1ml  $815.00

UCP1 / UCP-1 Antibody (aa179-296, Cy3) LS-C704401
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $365.00; 200µl  $445.00; 1ml  $1,080.00; 10ml  $4,320.00

UCP1 / UCP-1 Antibody (aa1-307) LS-C376983
Rabbit Polyclonal (IgG) to Human UCP1 / UCP-1
Human
ELISA IHC IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human testis using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human pancreas using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human testis using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human pancreas using antibody at 1:100 dilution.

UCP1 / UCP-1 Antibody (C-Terminus) LS-C10946
Rabbit Polyclonal (IgG) to Mouse UCP1 / UCP-1
Mouse, Rat
ELISA WB
Unconjugated
50µg  $445.00; 100µg  $755.00

UCP1 / UCP-1 Antibody LS-C334345
Rabbit Polyclonal (IgG) to Human UCP1 / UCP-1
Mouse, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cell lines, using UCP1 antibody.
Western blot analysis of extracts of various cell lines.
Western blot analysis of extracts of various cell lines, using UCP1 antibody.
Western blot analysis of extracts of various cell lines.

UCP1 / UCP-1 Antibody (clone 4B7) LS-C139052
Mouse Monoclonal [clone 4B7] (IgG2a,k) to Human UCP1 / UCP-1
Mouse, Human
ELISA WB
Unconjugated
50µg  $355.00
UCP1 monoclonal antibody (M03), clone 4B7. Western blot of UCP1 expression in NIH/3T3.
Detection limit for recombinant GST tagged UCP1 is approximately 3 ng/ml as a capture antibody.
UCP1 monoclonal antibody (M03), clone 4B7. Western blot of UCP1 expression in NIH/3T3.
Detection limit for recombinant GST tagged UCP1 is approximately 3 ng/ml as a capture antibody.

UCP1 / UCP-1 Antibody (aa179-296) LS-C296915
Rabbit Polyclonal (IgG) to Rat UCP1 / UCP-1
Rat
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00; 10ml 0.5mg/ml  $2,280.00
Western blot of recombinant UCP1 / UCP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant UCP1 / UCP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UCP1 / UCP-1 Antibody (aa179-296) LS-C373380
Rabbit Polyclonal (IgG) to Rat UCP1 / UCP-1
Rat
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00; 10ml 0.5mg/ml  $2,280.00
Western blot of UCP1 / UCP-1 antibody.
Western blot of UCP1 / UCP-1 antibody.
Showing 1-25 of 53 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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