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UCN3 / SPC

urocortin 3

UCN3 / SPC is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.

Gene Name: urocortin 3
Synonyms: UCN3, SPC, Stresscopin, Urocortin 3 (stresscopin), Urocortin 3, Urocortin III, Urocortin-3, UCNIII, SCP, Ucn III
Target Sequences: Q969E3 Q969E3

Publications (3)

1
Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise. Kavalakatt S, Khadir A, Madhu D, Hammad M, Devarajan S, Abubaker J, Al-Mulla F, Tuomilehto J, Tiss A. Frontiers in endocrinology. 2019 November;10: [Full Text Article] [PubMed:31781037] [PMC:PMC6851015]
2
Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Heikki A Koistinen , Fahd Al-Mulla, Jaakko Tuomilehto , Jehad Abubaker, Ali Tiss. Scientific reports. 2021 Aug;11:15666. [Full Text Article] [PubMed:34341463] [PMC:PMC8329193]
3
Circulating levels of urocortin neuropeptides are impaired in children with overweight. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Sriraman Devarajan, Samia Warsame, Hessa AlKandari, Maria AlMahdi, Heikki A Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Jehad Abubaker, Ali Tiss. Obesity (Silver Spring, Md.). 2022 Feburary;30:472-481. [Full Text Article] [PubMed:35088550] [PMC:PMC9305428]

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ELISA Kits (11)
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UCN3 / SPC (11)
Human (4)
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UCN3 / SPC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
UCN3 / SPC ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
UCN3 / SPC ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
UCN3 / SPC ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
UCN3 / SPC ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
0.938 - 60 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
UCN3 / SPC ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
UCN3 / SPC ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
UCN3 / SPC ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
UCN3 / SPC ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
UCN3 / SPC ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
UCN3 / SPC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).