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UBE2NL is intronless and encodes a member of the ubiquitin-conjugating enzyme family. The protein product is 91% identical to ubiquitin-conjugating enzyme E2N, a multi-exon gene product. This locus represents a polymorphic pseudogene, where some individuals contain an allele that can encode a full-length protein, while others have a non-functional allele containing a premature stop codon (reference SNP rs237520) that truncates the coding sequence.
Gene Name: | ubiquitin-conjugating enzyme E2N-like |
Synonyms: | UBE2NL, Li174 |
Target Sequences: | NP_001013007.1 Q5JXB2 |
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