UBE2A

ubiquitin-conjugating enzyme E2A

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

UBE2A (8)

Publications

No (8)

Tag

6His, N-terminus (1)

GST (1)

GST-6His, N-terminus (1)

His (2)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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UBE2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117409

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.1 kDa

Price:

100 µg/$494

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Human UBE2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80865

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.1 kDa

Price:

20 µg/$150

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Human UBE2A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67863

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.1 kDa

Price:

20 µg/$1,107

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Human UBE2A Protein (Recombinant His) (Met1-Cys152) - LS-G97997

Source:

E. coli

Tag:

His

Molecular Weight:

19.2 kDa

Price:

100 µg/$661

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Human UBE2A Protein (Recombinant 6His, N-terminus) (Met1-Cys152) - LS-G138681

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

49.0 kDa

Price:

10 µg/$322; 50 µg/$354

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Human UBE2A Protein (Recombinant GST) (Full Length) - LS-G30812

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

42.46 kDa

Price:

10 µg/$479; 25 µg/$670

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Human UBE2A Protein (Recombinant GST-6His, N-terminus) (Met1-Cys152) - LS-G38715

Source:

E. coli

Tag:

GST-6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

49kD

Price:

10 µg/$233; 50 µg/$266; 500 µg/$761; 1 mg/$1,067

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Human UBE2A Protein (Recombinant His) - LS-G777

Source:

E. coli

Tag:

His

Price:

100 µg/$342; 500 µg/$641; 20 µg/$254

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