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UBE2A

ubiquitin-conjugating enzyme E2A

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.

Gene Name: ubiquitin-conjugating enzyme E2A
Synonyms: UBE2A, HHR6A, HR6A, MRXSN, RAD6 homolog A, RAD6A, Ubiquitin carrier protein A, Ubiquitin-protein ligase A, MRXS30, UBC2
Target Sequences: NM_003336 NP_003327.2 P49459

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UBE2A (7)
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96-Well Strip Plate (5)
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UBE2A ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
UBE2A ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
UBE2A ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
UBE2A ELISA Kit
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Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
UBE2A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
UBE2A ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
UBE2A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).