UBA1 / UBE1

ubiquitin-like modifier activating enzyme 1

Ubiquitin Activating Enzyme (E1), also known as A1S9 and UBE1, is responsible for the first step in ubiquitin-protein isopeptide bond formation. E1 catalyzes the activation of the Cterminal carboxyl group of ubiquitin by forming a high-energy thioester bond in an ATP-dependent manner. UBE1 is monomeric and contains two active sites within the E1 molecule, allowing it to bind two ubiquitin moieties at a time, with a new ubiquitin forming an adenylate intermediate as the previous one is transferred to the thiol site. Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR. Isoform 1 has a different 5' noncoding exon compared to isoform 2. Both variants encode the same protein.

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Products

ELISA Kits (2)

Type

Competitive EIA (1)

Sandwich (1)

Target

UBA1 / UBE1 (2)

Reactivity

Human (1)

Rat (1)

Format

96-Well Strip Plate (2)

Publications

No (2)

Sample Type

Plasma (2)

Serum (2)

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Human UBA1 / UBE1 (Competitive EIA) ELISA Kit - LS-F27686

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

5 - 100 U/l

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Rat UBA1 / UBE1 (Sandwich ELISA) ELISA Kit - LS-F27421

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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