TXNIP

thioredoxin interacting protein

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

TXNIP (10)

Publications

No (10)

Tag

6His, N-terminus (1)

6His-B2M, N-terminus (2)

6His-SUMO, N-terminus (1)

GST, N-terminus (1)

His (1)

His-GST (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (3)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (5)

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Mouse TXNIP Protein (Recombinant 6His-B2M, N-terminus) (aa1-397) - LS-G56812

Source:

E. coli

Tag:

6His-B2M, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human TXNIP Protein (Recombinant GST, N-terminus) (Full Length) - LS-G32267

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

70.1 kDa

Price:

2 µg/$439

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Human TXNIP Protein (Recombinant His) (aa32-367) - LS-G24224

Source:

E. coli

Tag:

His

Molecular Weight:

41.1 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Mouse TXNIP Protein (Recombinant His-GST) (aa30-381) - LS-G24225

Source:

E. coli

Tag:

His-GST

Molecular Weight:

69.4 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Mouse TXNIP Protein (Recombinant 6His, N-terminus) (aa1-397) - LS-G57326

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human TXNIP Protein (Recombinant 6His-SUMO, N-terminus) (aa1-391) - LS-G56059

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

100 µg/$1,128; 20 µg/$721

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Human TXNIP Protein (Recombinant 6His-B2M, N-terminus) (aa1-391) - LS-G56060

Source:

E. coli

Tag:

6His-B2M, N-terminus

Price:

100 µg/$1,128; 20 µg/$721

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Human TXNIP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68069

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.5 kDa

Price:

20 µg/$1,107

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Human TXNIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81380

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.5 kDa

Price:

20 µg/$150

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TXNIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100829

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.5 kDa

Price:

100 µg/$494

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