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Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia.
Gene Name: | twinfilin actin-binding protein 2 |
Family/Subfamily: | Protein Kinase , A6 |
Synonyms: | TWF2, A6RP, A6-related protein, A6r, PTK9L, Twinfilin-1-like protein, Twinfilin-2, HA6RP, MSTP011, Protein tyrosine kinase 9-like |
Target Sequences: | NM_007284 NP_009215.1 Q6IBS0 |
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