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Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.
Gene Name: | twinfilin actin-binding protein 1 |
Family/Subfamily: | Protein Kinase , A6 |
Synonyms: | TWF1, A6, A6 protein tyrosine kinase, Protein A6, Twinfilin, Twinfilin-1, Protein tyrosine kinase, Protein tyrosine kinase 9, PTK9, PTK9 protein tyrosine kinase 9 |
Target Sequences: | NM_002822 NP_002813.3 Q12792 |
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