TTI1

TELO2 interacting protein 1

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

TTI1 (3)

Publications

No (3)

Tag

DDK,C-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Sf9 Cells (1)

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Human TTI1 Protein (Recombinant DDK,C-terminus) - LS-G142454

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

121.9 kDa

Price:

20 µg/$677

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TTI1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101246

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121.9 kDa

Price:

100 µg/$494

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Human TTI1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G95118

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121.9 kDa

Price:

20 µg/$150

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