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TTC5

tetratricopeptide repeat domain 5

Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.

Gene Name:	tetratricopeptide repeat domain 5
Synonyms:	TTC5, TPR repeat protein 5
Target Sequences:	NM_138376 NP_612385.2 Q8N0Z6

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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