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TSTA3 / GDP-L-Fucose Synthase

tissue specific transplantation antigen P35B

Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

Gene Name: tissue specific transplantation antigen P35B
Synonyms: TSTA3, 3-5 epimerase/4-reductase, FX, GDP-L-fucose synthase, SDR4E1, p35B, Protein FX
Target Sequences: NM_003313 NP_003304.1 Q13630

Publications (1)

1
Glycomic Profiling Highlights Increased Fucosylation in Pseudomyxoma Peritonei. Saarinen L, Nummela P, Leinonen H, Heiskanen A, Thiel A, Haglund C, Lepistö A, Satomaa T, Hautaniemi S, Ristimäki A. Molecular & cellular proteomics : MCP. 2018 November;17:2107-2118. [Full Text Article] [PubMed:30072579] [PMC:PMC6210226] Related Antibodies: LS-B9837.

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Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
TSTA3 / GDP-L-Fucose Synthase (10)
No (10)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Human (8)
Mouse (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (2)
TSTA3 /  GDP-L-Fucose Synthase Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TSTA3 /  GDP-L-Fucose Synthase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.7 kDa
100 µg/$494
TSTA3 /  GDP-L-Fucose Synthase Protein - 12.5% SDS-PAGE of human TSTA3 stained with Coomassie Blue
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Wheat Germ Extract
GST
62.3 kDa
10 µg/$479; 25 µg/$670
TSTA3 /  GDP-L-Fucose Synthase Protein - Recombinant Tissue Specific Transplantation Antigen P35B By SDS-PAGE
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E. coli
His-T7
39.6 kDa
10 µg/$289; 50 µg/$492; 100 µg/$787; 200 µg/$985; 1 mg/$2,123; 500 µg/$1,650; 5 mg/$3,445; 2 mg/$2,314
TSTA3 /  GDP-L-Fucose Synthase Protein - Recombinant Tissue Specific Transplantation Antigen P35B By SDS-PAGE
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E. coli
His-T7
39.6 kDa
10 µg/$285; 50 µg/$462; 100 µg/$740; 200 µg/$925; 1 mg/$2,047; 500 µg/$1,581; 5 mg/$3,235; 2 mg/$2,236
TSTA3 /  GDP-L-Fucose Synthase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35.7 kDa
20 µg/$150
TSTA3 /  GDP-L-Fucose Synthase Protein - Purified recombinant protein TSTA3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
35.7 kDa
20 µg/$1,107
TSTA3 /  GDP-L-Fucose Synthase Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
37.0 kDa
10 µg/$344; 50 µg/$584
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E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.96kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).