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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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TSN / Translin

translin

TSN / Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.

Gene Name: translin
Synonyms: TSN, C3PO, BCLF-1, REHF-1, TBRBP, TRSLN, RCHF1, Translin
Target Sequences: NM_004622 NP_004613.1


TSN / Translin Antibody - Anti-Translin antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
TSN / Translin Antibody - Anti-TSN / Translin antibody IHC staining of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
TSN / Translin Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
TSN / Translin Antibody - TSN Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human TSN / Translin
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, IP, WB
Unconjugated
100µg   $435.00
TSN / Translin Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TSN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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Mouse Monoclonal [clone OTI1B5] (IgG2a) to Human TSN / Translin
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $345.00
TSN / Translin Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TSN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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Mouse Monoclonal [clone OTI1B5] (IgG2a) to Human TSN / Translin
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Human
IF, IHC, WB
Unconjugated
100µl   $295.00; 200µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
TSN / Translin Antibody - Western blot of Translin antibody
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Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
TSN / Translin Antibody - IHC of Translin (E121) pAb in paraffin-embedded human brain tissue.
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Rabbit Polyclonal to Human TSN / Translin
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl   $345.00
TSN / Translin Antibody - Immunohistochemical analysis of Translin staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human TSN / Translin
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
TSN / Translin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed
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Mouse Monoclonal [clone OTI4C6] (IgG1) to Human TSN / Translin
Human
WB
Unconjugated
100µl   1mg/ml   $345.00
TSN / Translin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TSN. (1:2000)
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Mouse Monoclonal [clone OTI4C6] (IgG1) to Human TSN / Translin
Human
WB
Unconjugated, Carrier-free
100µg   $395.00
TSN / Translin Antibody - Detection of human and mouse TSN by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-TSN antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Human
IP, WB
Unconjugated
100µl   1mg/ml   $405.00
TSN / Translin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed
Select
Mouse Monoclonal [clone OTI8F9] (IgG1) to Human TSN / Translin
Human
WB
Unconjugated
100µl   1mg/ml   $345.00
TSN / Translin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TSN. (1:2000)
Select
Mouse Monoclonal [clone OTI8F9] (IgG1) to Human TSN / Translin
Human
WB
Unconjugated, Carrier-free
100µg   $395.00
TSN / Translin Antibody - TSN / Translin antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human TSN / Translin
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
TSN / Translin Antibody - TSN / Translin antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human TSN / Translin
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).