Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Reasearch Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

TSN / Translin

translin

TSN / Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.

Gene Name: translin
Synonyms: TSN, C3PO, BCLF-1, REHF-1, TBRBP, TRSLN, RCHF1, Translin
Target Sequences: NM_004622 NP_004613.1

Filtered by: None
Target
TSN / Translin (27)
Reactivity
Human (27)
Mouse (13)
Rat (10)
Bat (4)
Bovine (5)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Hamster (4)
Horse (4)
Monkey (4)
Pig (4)
Rabbit (4)
Application
IHC (18)
IHC-P (5)
WB (27)
ELISA (11)
IF (4)
IP (2)
Peptide-ELISA (1)
Host
rabbit (21)
mouse (6)
Isotype
IgG (14)
IgG1 (4)
IgG2a (2)
Clonality
monoclonal mc (6)
polyclonal pc (21)
Clone
OTI1B5 (2)
OTI4C6 (2)
OTI8F9 (2)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (3)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (18)
Epitope
aa109-138 (8)
aa1-51 (6)
aa113-162 (4)
70-150 aa, Internal (1)
Glu121 (1)
Internal (1)
aa101-150 (1)
aa150-200 (1)
Publications
No (27)
Showing 1-25 of 27 results

IHC-plus™ TSN / Translin Antibody (aa101-150) LS-B8418
Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-Translin antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Western blot analysis of lysates from Jurkat cells, using TSN Antibody. The lane on the right is blocked with the synthesized peptide.

IHC-plus™ TSN / Translin Antibody LS-B9516
Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-TSN / Translin antibody IHC staining of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TSN / Translin antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TSN / Translin Antibody LS-C810203
Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

TSN / Translin Antibody (aa109-138) LS-C160257
Rabbit Polyclonal to Human TSN / Translin
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
TSN Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Fluorescent confocal image of HeLa cell stained with TSN Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with TSN primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). TSN immunoreactivity is localized to Nucleus and Cytoplasm significantly.

TSN / Translin Antibody LS-C661307
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, IP, WB
Unconjugated
100µg  $435.00

TSN / Translin Antibody (aa1-51, clone OTI1B5) LS-C794719
Mouse Monoclonal [clone OTI1B5] (IgG2a) to Human TSN / Translin
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TSN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TSN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)

TSN / Translin Antibody (aa1-51, clone OTI1B5, Carrier-free) LS-C798643
Mouse Monoclonal [clone OTI1B5] (IgG2a) to Human TSN / Translin
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TSN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-TSN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)

TSN / Translin Antibody LS-C411318
Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Human
IF, IHC, WB
Unconjugated
100µl  $295.00; 200µl  $385.00

TSN / Translin Antibody (aa109-138) LS-C326044
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

TSN / Translin Antibody (aa109-138, Biotin) LS-C207822
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

TSN / Translin Antibody (aa109-138, FITC) LS-C207823
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

TSN / Translin Antibody (aa109-138, AP) LS-C207819
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

TSN / Translin Antibody (aa109-138, APC) LS-C207821
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

TSN / Translin Antibody (aa109-138, Azide-free, HRP) LS-C207825
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

TSN / Translin Antibody (aa109-138, PE) LS-C207826
Rabbit Polyclonal (IgG) to Human TSN / Translin
Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

TSN / Translin Antibody (70-150 aa, Internal) LS-C386491
Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of Translin antibody

TSN / Translin Antibody (Glu121) LS-C176936
Rabbit Polyclonal to Human TSN / Translin
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of Translin (E121) pAb in paraffin-embedded human brain tissue.
Western blot of Translin (E121) pAb in extracts from Jurkat cells.

TSN / Translin Antibody (Internal) LS-C354107
Rabbit Polyclonal to Human TSN / Translin
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of Translin staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of Translin expression in MCF7 (A); HeLa (B); HepG2 (C) whole cell lysates.

TSN / Translin Antibody (aa1-51, clone OTI4C6) LS-C794776
Mouse Monoclonal [clone OTI4C6] (IgG1) to Human TSN / Translin
Human
WB
Unconjugated
100µl 1mg/ml  $345.00
HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed
HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed

TSN / Translin Antibody (aa1-51, clone OTI4C6, Carrier-free) LS-C791949
Mouse Monoclonal [clone OTI4C6] (IgG1) to Human TSN / Translin
Human
WB
Unconjugated, Carrier-free
100µg  $395.00
HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TSN. (1:2000)
Equivalent amounts of cell lysates  and TSN-Knockout Hela cells  were separated by SDS-PAGE and immunoblotted with anti-TSN monoclonal antibodyThen the blotted membrane was stripped and reprobed with anti-HSP90AB1 antibody  as a loading control. (1:200)

TSN / Translin Antibody (aa150-200) LS-C762889
Rabbit Polyclonal (IgG) to Human TSN / Translin
Mouse, Human
IP, WB
Unconjugated
100µg 100µl 1mg/ml  $395.00
Detection of human and mouse TSN by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-TSN antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

TSN / Translin Antibody (aa1-51, clone OTI8F9) LS-C794778
Mouse Monoclonal [clone OTI8F9] (IgG1) to Human TSN / Translin
Human
WB
Unconjugated
100µl 1mg/ml  $345.00
HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed
HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed

TSN / Translin Antibody (aa1-51, clone OTI8F9, Carrier-free) LS-C791948
Mouse Monoclonal [clone OTI8F9] (IgG1) to Human TSN / Translin
Human
WB
Unconjugated, Carrier-free
100µg  $395.00
HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY TSN. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TSN. (1:2000)

TSN / Translin Antibody (aa113-162) LS-C146174
Rabbit Polyclonal to Human TSN / Translin
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
TSN / Translin antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TSN / Translin Antibody (aa113-162, HRP) LS-C471018
Rabbit Polyclonal to Human TSN / Translin
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
TSN / Translin antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 27 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).