TSC501 / NAT8

N-acetyltransferase 8 (GCN5-related, putative)

Acetylates the free alpha-amino group of cysteine S-conjugates to form mercapturic acids (PubMed:20392701). This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates. The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile. Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241).

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

TSC501 / NAT8 (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human TSC501 / NAT8 Protein (Recombinant GST) (Full Length) - LS-G31441

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.71 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TSC501 / NAT8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68613

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.4 kDa

Price:

20 µg/$1,107

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Human TSC501 / NAT8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82619

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.4 kDa

Price:

20 µg/$150

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TSC501 / NAT8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100186

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.4 kDa

Price:

100 µg/$494

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