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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Additional Contact Details
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TS / Thromboxane Synthase
thromboxane A synthase 1 (platelet)
TS / Thromboxane Synthase encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | thromboxane A synthase 1 (platelet) |
| Synonyms: | TBXAS1, BDPLT14, CYP5, CYP5A1, Cytochrome P450 5A1, GHOSAL, Thromboxane Synthase, Thromboxane-A synthase, TS, TXAS, TXS, THAS, TXA synthase |
| Target Sequences: | NM_001061 NP_001052.2 P24557 |
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