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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TRPM4

transient receptor potential cation channel, subfamily M, member 4

Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca2+, it is impermeable to it. Mediates transport of monovalent cations (Na+ > K+ > Cs+ > Li+), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca2+ overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.

Gene Name: transient receptor potential cation channel, subfamily M, member 4
Family/Subfamily: Ion Channel , Calcium channel - TRP
Synonyms: TRPM4, HTRPM4, LTrpC-4, PFHB1B, Melastatin-4, TRPM4B, LTrpC4
Target Sequences: NM_017636 NP_060106.2 Q8TD43

Filtered by: None
Target
TRPM4 (46)
Reactivity
Human (44)
Mouse (15)
Rat (12)
Bat (1)
Bovine (12)
Chicken (1)
Chimpanzee (3)
Dog (6)
Gibbon (3)
Guinea pig (1)
Hamster (1)
Horse (5)
Monkey (5)
Pig (1)
Sheep (1)
Application
IHC (31)
IHC-P (27)
WB (23)
ELISA (8)
Host
rabbit (38)
mouse (8)
Isotype
IgG (10)
IgG1 (8)
Clonality
monoclonal mc (8)
polyclonal pc (38)
Clone
OTI10H5 (2)
OTI14C3 (2)
OTI14F1 (2)
OTI3C4 (2)
Format
AP Conjugated (4)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (5)
Carrier-free (4)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (19)
Epitope
aa1121-1149 (8)
C-Terminus (7)
Internal (7)
N-Terminus (7)
aa359-408 (4)
aa1079-1214 (1)
aa500-600 (1)
Publications
No (45)
Yes (1)
Showing 1-25 of 46 results

IHC-plus™ TRPM4 Antibody (Internal) LS-A8605
Publications (1)
Publications (1)
Rabbit Polyclonal to Human TRPM4
Mouse, Bovine, Rat, Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-TRPM4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (Internal, AP) LS-A108113
Rabbit Polyclonal to Human TRPM4
Mouse, Bovine, Rat, Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (Internal, Azide-free, HRP) LS-A108117
Rabbit Polyclonal to Human TRPM4
Mouse, Bovine, Rat, Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-TRPM4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (N-Terminus) LS-A8602
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-TRPM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (N-Terminus, Biotin) LS-A108109
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (N-Terminus, FITC) LS-A108110
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (N-Terminus, AP) LS-A108107
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (N-Terminus, APC) LS-A108108
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (N-Terminus, Azide-free, HRP) LS-A108111
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-TRPM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (N-Terminus, PE) LS-A108112
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (C-Terminus) LS-A8616
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-TRPM4 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (C-Terminus, Biotin) LS-A108121
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (C-Terminus, FITC) LS-A108122
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (C-Terminus, APC) LS-A108120
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (C-Terminus, AP) LS-A108119
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (C-Terminus, Azide-free, HRP) LS-A108123
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-TRPM4 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRPM4 Antibody (C-Terminus, PE) LS-A108124
Rabbit Polyclonal to Human TRPM4
Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-TRPM4 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPM4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TRPM4 Antibody (aa1079-1214) LS-C408114
Rabbit Polyclonal to Human TRPM4
Chicken, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Human
IHC, IHC-P, WB
Unconjugated
100µg  $355.00
TRPM4 was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti- TRPM4 Antigen Affinity purified polyclonal antibody at 1 ug/mL. The immunohistochemical section was developed using SABC method.
Western blot analysis of TRPM4 expression in mouse spleen extract (lane 1) and SW620 whole cell lysates (lane 2). TRPM4 at 134 kD was detected using rabbit anti- TRPM4 Antigen Affinity purified polyclonal antibody at 0.5 ug/mL. The blot was developed using chemiluminescence (ECL) method.

TRPM4 Antibody (clone OTI3C4) LS-C114479
Mouse Monoclonal [clone OTI3C4] (IgG1) to Human TRPM4
Human
WB
Unconjugated
100µl 1.2mg/ml  $345.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRPM4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRPM4.

TRPM4 Antibody (clone OTI10H5) LS-C114489
Mouse Monoclonal [clone OTI10H5] (IgG1) to Human TRPM4
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded liver tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).

TRPM4 Antibody (clone OTI10H5, Carrier-free) LS-C784213
Mouse Monoclonal [clone OTI10H5] (IgG1) to Human TRPM4
Dog, Human, Monkey
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded liver tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).

TRPM4 Antibody (clone OTI14F1) LS-C114485
Mouse Monoclonal [clone OTI14F1] (IgG1) to Human TRPM4
Human
IHC, IHC-P, WB
Unconjugated
100µl 0.8mg/ml  $345.00
IHC of paraffin-embedded liver tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).
IHC of paraffin-embedded pancreas tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).

TRPM4 Antibody (clone OTI14F1, Carrier-free) LS-C784207
Mouse Monoclonal [clone OTI14F1] (IgG1) to Human TRPM4
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
IHC of paraffin-embedded liver tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).
IHC of paraffin-embedded pancreas tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).

TRPM4 Antibody (clone OTI14C3) LS-C114478
Mouse Monoclonal [clone OTI14C3] (IgG1) to Human TRPM4
Human
IHC, IHC-P, WB
Unconjugated
100µl 0.7mg/ml  $345.00
IHC of paraffin-embedded liver tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).
IHC of paraffin-embedded Carcinoma of liver tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).

TRPM4 Antibody (clone OTI14C3, Carrier-free) LS-C784201
Mouse Monoclonal [clone OTI14C3] (IgG1) to Human TRPM4
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
IHC of paraffin-embedded liver tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).
IHC of paraffin-embedded Carcinoma of liver tissue using anti-TRPM4 mouse monoclonal antibody. (Dilution 1:50).
Showing 1-25 of 46 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).