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TRIP10 / CIP4

thyroid hormone receptor interactor 10

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling By similarity. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Gene Name: thyroid hormone receptor interactor 10
Synonyms: TRIP10, Cdc42-interacting protein 4, Protein Felic, Salt tolerator, STOT, STP, TR-interacting protein 10, Salt tolerant protein, CIP4, HSTP, TRIP-10
Target Sequences: NM_004240 NP_004231.1 Q15642

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
TRIP10 / CIP4 (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
TRIP10 / CIP4 Protein - 12.5% SDS-PAGE of human TRIP10 stained with Coomassie Blue
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Wheat Germ Extract
GST
89 kDa
10 µg/$479; 25 µg/$670
TRIP10 / CIP4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
62.4 kDa
100 µg/$494
TRIP10 / CIP4 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
TRIP10 / CIP4 Protein - Purified recombinant protein TRIP10 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
62.4 kDa
20 µg/$1,107
TRIP10 / CIP4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
62.4 kDa
20 µg/$150
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).