TRIM72 / MG53

tripartite motif containing 72

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca2+-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.

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Products

Proteins (11)

Type

Over-Expression Lysate (2)

Recombinant (9)

Target

TRIM72 / MG53 (11)

Publications

No (11)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Myc-DDK (Flag), C-terminus (1)

Species

Human (10)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (5)

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Human TRIM72 / MG53 Protein (Recombinant Myc-DDK (Flag), C-terminus) (aa1-269) - LS-G57077

Source:

Mammalian Cells

Tag:

Myc-DDK (Flag), C-terminus

Price:

20 µg/$431

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TRIM72 / MG53 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121915

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.6 kDa

Price:

100 µg/$710

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Human TRIM72 / MG53 Protein (Recombinant) - LS-G143834

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

52.6 kDa

Price:

50 µg/$520

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Human TRIM72 / MG53 Protein (Recombinant) - LS-G143835

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

52.6 kDa

Price:

50 µg/$520

Select

Human TRIM72 / MG53 Protein (Recombinant) - LS-G143850

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

29.6 kDa

Price:

50 µg/$520

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Human TRIM72 / MG53 Protein (Recombinant) - LS-G143851

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

23.1 kDa

Price:

50 µg/$520

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Human TRIM72 / MG53 Protein (Recombinant) - LS-G143852

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

40.2 kDa

Price:

50 µg/$520

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Human TRIM72 / MG53 Protein (Recombinant GST) (Full Length) - LS-G37523

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TRIM72 / MG53 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72858

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.6 kDa

Price:

20 µg/$1,107

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Human TRIM72 / MG53 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93766

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.6 kDa

Price:

20 µg/$215

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Human TRIM72 / MG53 Protein (Recombinant GST, N-terminus) (aa378-477) - LS-G63968

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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