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TRIM69 / Trif
tripartite motif containing 69
TRIM69 / Trif is a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
| Gene Name: | tripartite motif containing 69 |
| Family/Subfamily: | Tripartite Motif |
| Synonyms: | TRIM69, HSD34, TRIF, TRIMLESS, Tripartite motif containing 69, RING finger protein 36, Tripartite motif protein 69, Tripartite motif-containing 69, RNF36 |
| Target Sequences: | NM_182985 NP_892030.3 Q86WT6 |
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